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![Medchemexpress LLC 10H-Thieno[2,3-b]benzodiazepine, 2-methyl-4-(4-methyl-1-piperazinyl)-](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-650.jpg)
Medchemexpress LLC 10H-Thieno[2,3-b]benzodiazepine, 2-methyl-4-(4-methyl-1-piperazinyl)- | 132539-06-1 | 99.4% | C17H20N4S | 50 MG
Supplier: Medchemexpress LLC HY1454150MG
Olanzapine (LY170053) is a selective, orally active monoaminergic antagonist. It demonstrates high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6, dopamine D1-4, muscarinic M1-5, and adrenergic α1 receptors. Olanzapine is recognized as an atypical antipsychotic.
- Selective, orally active monoaminergic antagonist
- High affinity binding to serotonin, dopamine, muscarinic, and adrenergic α1 receptors
- Induces autophagy in human SH-SY5Y neuronal cells
- Exhibits anti-proliferative effects in glioblastoma cell lines
- Enhances Temozolomide's anti-tumor activity
- Induces apoptosis and necrosis in glioblastoma cell lines
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