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Apexbio Technology LLC Olprinone Hydrochloride 119615-63-3 100mg
Supplier: Apexbio Technology LLC A3683100
Olprinone Hydrochloride (CAS 119615-63-3) is a small-molecule inhibitor that selectively targets phosphodiesterase 3 (PDE3) leading to increased intracellular cyclic adenosine monophosphate (cAMP) levels This mechanism confers both positive inotropic effects enhancing cardiac contractility and vasodilatory properties supporting improved hemodynamics Olprinone has demonstrated benefits in augmenting cardiac output particularly during the post-cardiopulmonary bypass phase and has been administered at infusion rates of 0 2 g/kg/min in this context Additionally it has shown activity in improving microcirculatory flow and mitigating inflammatory and oxidative responses such as in models of meconium-induced lung injury These attributes highlight its utility in cardiovascular and inflammation-related biomedical research
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