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CPC Scientific H-Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Met-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys-NH2 (acetate salt) 1MG
SDP

Supplier:  CPC Scientific TOXI002B

Encompass

Reversible N-type Ca2+ Channel Blocker -Conotoxin MVIIA, originally isolated from the venom of the fish-hunting cone snail Conus magus, is a blocker of voltage-sensitve Ca2+ channels in neurons. It has been used to identify different Ca2+ channel subtypes in amphibian brain.SEQUENCE: H-Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Met-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys-NH2 (acetate salt)(Disulfide bridge: Cys1-Cys16, Cys8-Cys20, and Cys15-Cys25)ONE-LETTER SEQUENCE: CKGKGAKCSRLMYDCCTGSCRSGKC-NH2 (Disulfide bridge: 1-16, 8-20, and 15-25)MOLECULAR FORMULA: C102H172N36O32S7MOLECULAR WEIGHT: 2639.1STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [107452-89-1]SYNONYMS: Ziconotide, SNX-111RESEARCH AREA: ToxinREFERENCES:Olivera, BM. et al. Biochem. 26, 2086 (1987)Hillyard, DR. et al. Neuron. 9, 69 (1992).)B.M. Olivera, L.J. Cruz, V. de Santos, G.W. Le Cheminant, D. Griffin, R. Zeikus, J.M. McIntosh, R. Galyean, J. Varga, W.R. Gray, and J. Rivier, Bioche

Catalog No. 50-211-0584


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