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Medchemexpress LLC Oncrasin-72 (NSC-743380) | 92407-90-4 | 97.6% | 25 MG
Supplier: Medchemexpress LLC 25MGHY130207
Oncrasin-72 (NSC-743380) is an RNA polymerase II inhibitor that demonstrates activity in inhibiting growth and inducing cell death in human cancer cells. It exhibits antitumor activity by activating JNK and inhibiting STAT3. Analytical method development and validation for Oncrasin-72 is crucial for quantifying its concentration in biological fluids for pharmacokinetic studies, and a method has successfully quantified Oncrasin-72 in rat plasma across different dose groups. The product is for research use only and has not been fully validated for medical applications.
- RNA polymerase II inhibitor
- Inhibits growth in human cancer cells
- Induces cell death in human cancer cells
- Exhibits antitumor activity
- Activates JNK
- Inhibits STAT3
- Quantifiable in biological fluids for pharmacokinetic studies
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