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Medchemexpress LLC Ont-093 (oc 144-093) | 216227-54-2 | C32H38N4O | 1 MG
SDP

Supplier:  Medchemexpress LLC HY151341MG

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ONT-093 (OC 144-093) is a potent and orally active inhibitor of the P-glycoprotein pump, which mediates drug efflux and impacts bioavailability. It inhibits P-gp-mediated ATPase activity with an IC50 of 0.16 μM. This compound is capable of reversing multidrug resistance in cancer cells to chemotherapeutic drugs, making it suitable for research in cancer, such as colon cancer, and infections like malaria.

  • Potent and orally active inhibitor of P-glycoprotein pump.
  • Inhibits P-gp-mediated ATPase activity (IC50 of 0.16 μM).
  • Reverses multidrug resistance in cancer cells to chemotherapeutic drugs.
  • Useful for research in cancer and infections like malaria.
  • Shows no significant cytotoxicity against normal and tumor cell lines.

Catalog No. 50-003-75937


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