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Medchemexpress LLC Osilodrostat (phosphate) | 1315449-72-9 | 98.8% | 325.23 | 25 MG
Supplier: Medchemexpress LLC 25MGHY16276A
Osilodrostat phosphate is a potent, orally active 11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM. It also acts as a potent, orally active aldosterone synthase (CYP11B2) inhibitor. This compound inhibits aldosterone and corticosterone synthesis and has blood pressure-lowering ability, making it suitable for research related to Cushing syndrome (CS).
- Inhibits cortisol and aldosterone in various cell types.
- Reduces mean arterial pressure in animal models.
- Used in research for Cushing syndrome.
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