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Rockland Immunochemicals OspA Control Protein 100 µg
SDP

Supplier:  Rockland Immunochemicals 000001C13

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Outer-Surface Protein A (OspA) a lipoprotein from Borrelia burgdorferi encoded on its Plasmid lp54 is a major component of the spirochete's extracellular matrix. OspA probably serves as a lipid-anchor. The spirochetes migrate from the tick midgut during feeding to its salivary glands and are thus transmitted to the mammal host. This transition may be facilitated by changes in expression of some B. burgdorferi genes. Upon transmission of the spirochete from the Ixodes tick to mammalian host the transcript level of OspA can change. B. burgdorferi can attach to diverse tissues within the vertebrate host and the tick vector suggesting that physiological factors other than pH and temperature may play roles in modulating B. burgdorferi gene expression.

Catalog No. 50-194-3746


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