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Medchemexpress LLC OT-82 | 1800487-55-1 | 99.9% | 424.47 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY136241100MG

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OT-82 is a potent, selective, and orally active inhibitor of NAMPT. It is selectively toxic to cells of hematopoietic origin and induces cell death in a NAD+ dependent manner, making it a promising antineoplastic agent for the study of hematological malignancies. This product is for research use only.

  • Potent, selective, and orally active NAMPT inhibitor.
  • Selectively toxic to cells of hematopoietic origin.
  • Induces cell death in a NAD+ dependent manner.
  • Promising antineoplastic agent for hematological malignancies.
  • Exhibits hallmarks of apoptotic cell death.
  • Inhibits recombinant NAMPT activity and reduces cellular NAD and ATP concentrations.
  • Potently inhibited tumor growth in a multiple myeloma mouse model.

Catalog No. 50-003-52010


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