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Medchemexpress LLC OT-82 | 1800487-55-1 | 99.9% | 424.47 | 100 MG

Supplier: Medchemexpress LLC HY136241100MG
OT-82 is a potent, selective, and orally active inhibitor of NAMPT. It is selectively toxic to cells of hematopoietic origin and induces cell death in a NAD+ dependent manner, making it a promising antineoplastic agent for the study of hematological malignancies. This product is for research use only.
- Potent, selective, and orally active NAMPT inhibitor.
- Selectively toxic to cells of hematopoietic origin.
- Induces cell death in a NAD+ dependent manner.
- Promising antineoplastic agent for hematological malignancies.
- Exhibits hallmarks of apoptotic cell death.
- Inhibits recombinant NAMPT activity and reduces cellular NAD and ATP concentrations.
- Potently inhibited tumor growth in a multiple myeloma mouse model.
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