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Medchemexpress LLC Oxamic acid sodium (sodium oxamate) | 565-73-1 | 99.7% | 111.03 | 1 G
Supplier: Medchemexpress LLC HYW013032A1G
Oxamic acid sodium salt is a lactate dehydrogenase-A (LDH-A) inhibitor that exhibits anti-tumor and anti-proliferative activity against cancer cells, and can induce apoptosis.
- Inhibits proliferation, migration, and invasion of A2780 and SKOV3 cells.
- Induces cell cycle arrest in G2/M phase.
- Promotes apoptosis via caspase-3 activation and mitochondrial pathway.
- Increases reactive oxygen species (ROS) levels in NPC cells.
- Enhances tumor inhibition in vivo when combined with irradiation.
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