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Medchemexpress LLC P 22077 | 1247819-59-5 | 98.42% | 315.32 | 10 MG
Supplier: Medchemexpress LLC 10MGHY13865
P 22077 is a cell-permeable inhibitor targeting ubiquitin-specific protease 7 (USP7) with an EC50 of 8.01 μM, and USP47 with an EC50 of 8.74 μM. This compound demonstrates antiproliferative activity against human HCT116 cells and induces p53-mediated apoptosis in neuroblastoma cells, highlighting its potential for anticancer research.
- Cell-permeable USP7 and USP47 inhibitor
- Inhibits USP7 with an EC50 of 8.01 μM
- Inhibits USP47 with an EC50 of 8.74 μM
- Shows antiproliferative activity against human HCT116 cells
- Induces p53-mediated apoptosis in neuroblastoma cells
- Exhibits antitumor effects in xenograft mouse models
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