Medchemexpress LLC P38 MAP kinase inhibitor III | 581098-48-8 | MFCD09037547 | 98.8% | 404.50 g/mol | C23H21FN4S | 5 MG

Supplier:  Medchemexpress LLC HY1123895MG

p38 MAP Kinase Inhibitor III is a small-molecule inhibitor of p38 mitogen-activated protein kinase (p38 MAPK) for research use. It shows in vitro activity (IC50 ≈ 0.9 μM) and reduces proinflammatory cytokine release, provided as a solid with high purity and documented solubility and storage conditions for both in vitro and in vivo formulations.

• Inhibits p38 MAP kinase (IC50 ≈ 0.9 μM).
• Reduces IL-1β and TNF-α release (IC50 0.37 μM and 0.044 μM).
• High purity suitable for research applications.
• Good solubility in DMSO and DMF for stock solutions.
• Formulatable for in vivo dosing at ≥ 5 mg/mL in recommended vehicles.
• Stable as a powder at -20°C for long-term storage.

Catalog No. 50-002-64219