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Enzo Life Sciences Paclitaxel (25 mg). CAS: 33069-62-4
Supplier: Enzo Life Sciences BMLT1040025
Antitumor agent. Stabilizes microtubules and lowers the critical concentration for tubulin polymerization. Reversibly binds to polymerized tubulin. Inhibits protein isoprenylation and induces apoptosis in PC-3 human prostate cancer cells. The checkpoint of mitotic spindle assembly, aberrant activation of cyclin-dependent kinases (CKDs) and the c-Jun N-terminal kinase/stress activated protein kinase (JNK/SAPK) are involved in Paclitaxel-induced apoptosis. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO or methanol at 10mg/ml. Long Term Storage: -20°C.
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