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Cayman Chemical PaclItaxel octadecndIoate 10mg
SDP

Supplier:  Cayman Chemical 2863510 MG

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A prodrug form of paclitaxel; comprised of paclitaxel conjugated to 1,18-octadecanedioic acid; does not promote tubulin polymerization in vitro at 10 μM; cytotoxic to HT-1080, PANC-1, and HT-29 cells (IC50 = 12, 2.48, and 8.62 nM, respectively) as a 5:1 mixture with HSA; mixture with HSA reduces tumor growth and increases survival in an HT-1080 mouse xenograft model in a dose-dependent manner

Catalog No. 50-293-8149


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