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Cayman Chemical PalmItoyl SerInol 10mg

Supplier: Cayman Chemical 6217510 MG
A derivative of 2-palmitoyl glycerol and agonist of GPR119 (EC50 = 9 µM for increasing cAMP levels in HEK293 cells expressing GPR119); reduces IL-4-induced decreases in the levels of long-chain fatty acid-containing ceramides in IL-4-stimulated HaCaT keratinocytes; binds to PKCζ and induces apoptosis in F-11 neuroblastoma cells (IC50 = ~80 µM) in a PKCζ-dependent manner at 25 µM
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