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Medchemexpress LLC Pamoic acid (Embonic acid) | 130-85-8 | 99.7% | 388.38 | 1 G
SDP

Supplier:  Medchemexpress LLC HYW0086131G

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Pamoic acid (Embonic acid) is a potent GPR35 agonist with an EC50 of 79 nM. It exhibits neuroprotective and anti-inflammatory properties. GPR35 activation by Pamoic acid may increase the phosphorylation of ERK1/2, which suppresses NF-κB-dependent inflammatory genes.

  • Potent GPR35 agonist with an EC50 of 79 nM.
  • Exhibits neuroprotective properties.
  • Exhibits anti-inflammatory properties.
  • Activates GPR35 to increase phosphorylation of ERK1/2.
  • Suppresses NF-κB-dependent inflammatory genes.
  • Reduces infarct size in a GPR35 dependent manner.
  • Increases noninflammatory Ly-6CLo monocytes/macrophages in ischemic brain.
  • Reduces neutrophil counts.

Catalog No. 50-004-52180


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