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Medchemexpress LLC Pamoic acid | 130-85-8 | 99.7% | 388.38 | 50 G
SDP

Supplier:  Medchemexpress LLC HYW00861350G

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Pamoic acid (Embonic acid) is a potent GPR35 agonist with an EC50 of 79 nM. It exhibits neuroprotective and anti-inflammatory properties, making it suitable for research into neurological and inflammatory diseases.

  • Potent GPR35 agonist with an EC50 of 79 nM.
  • Exhibits neuroprotective and anti-inflammatory properties.
  • GPR35 activation may increase phosphorylation of ERK1/2, suppressing NF-κB-dependent inflammatory genes.
  • Shows neuroprotective activity by activating GPR35, reducing infarct size in mouse stroke models.
  • Increases noninflammatory Ly-6CLo monocytes/macrophages and reduces neutrophil counts in the ischemic brain.

Catalog No. 50-004-52181


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