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Medchemexpress LLC Pamoic acid | 130-85-8 | 99.7% | 388.38 | 50 G

Supplier: Medchemexpress LLC HYW00861350G
Pamoic acid (Embonic acid) is a potent GPR35 agonist with an EC50 of 79 nM. It exhibits neuroprotective and anti-inflammatory properties, making it suitable for research into neurological and inflammatory diseases.
- Potent GPR35 agonist with an EC50 of 79 nM.
- Exhibits neuroprotective and anti-inflammatory properties.
- GPR35 activation may increase phosphorylation of ERK1/2, suppressing NF-κB-dependent inflammatory genes.
- Shows neuroprotective activity by activating GPR35, reducing infarct size in mouse stroke models.
- Increases noninflammatory Ly-6CLo monocytes/macrophages and reduces neutrophil counts in the ischemic brain.
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