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Medchemexpress LLC Pancuronium (dibromide) | 15500-66-0 | 98.0% | 50 MG
SDP

Supplier:  Medchemexpress LLC HYB042950MG

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Pancuronium dibromide is a bis-quaternary steroid and a neuromuscular relaxant. It inhibits neuromuscular transmission by competing with acetylcholine for binding sites on nACh receptors, inhibits cardiac muscarinic receptors, and exhibits a sympathomimetic action. This compound is intended for research use only.

  • Inhibits neuromuscular transmission by competing with acetylcholine for binding sites on nACh receptors
  • Inhibits cardiac muscarinic receptors
  • Exhibits sympathomimetic action
  • Blocks SKCa channels, with an IC50 of 6.8 μM for inhibiting after hyperpolarization (AHP) in sympathetic neurons
  • Reversibly inhibits transmembrane sodium conductance in dorsal root ganglion neurons
  • Abolishes bradycardia induced by acetylcholine and vagal nerve stimulation in guinea pigs

Catalog No. 50-004-08921


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