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Bachem PAR-4 (1-6) amide (mouse) Trifluoroacetate

Supplier: Bachem 4035649.0005
PAR-4 (1-6) amide (mouse) Trifluoroacetate, H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2, 245443-52-1, C33H46N8O7, Mr 666.78, 5mg. Thrombin Receptor-Like 3 (1-6) amide (mouse), Proteinase Activated Receptor 4 (1-6) amide (mouse), Coagulation Factor II Receptor-Like 3 (1-6) amide (mouse), GYPGKFamide, GYPGKF-NH2 Selective Protease-Activated Receptor 4 (PAR4) Agonist. Protease-activated receptor-4 activating peptide derived from murine PAR-4. GYPGKF-amide was able to cause rat platelet aggregation with an EC50 value of 40 uM. Its effect on leucocyte rolling and adherence points at a role of PAR-4 in mediating proinflammatory processes.
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