Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
CPC Scientific H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2 (trifluoroacetate salt) 5MG
Supplier: CPC Scientific PARP014A
Protease-activated receptor-4 activating peptide derived from murine PAR-4. This peptide was able to cause rat platelet aggregation with an EC50 value of 40 ?M. Its effect on leucocyte rolling and adherence points at a role of PAR-4 in mediating proinflammatory processes. The family of at least seven transmembrane G protein coupled receptors includes at least four receptor subtypes (PAR1, PAR2, PAR3, PAR4). PAR4 activating peptides, GYPGKF-NH2 and AYPGKG-NH2, produce concentration dependent contractile effects on the muscle.ONE-LETTER SEQUENCE: GYPGKF-NH2MOLECULAR FORMULA: C33H46N8O7MOLECULAR WEIGHT:666.78STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [245443-52-1], RESEARCH AREA: HematologyREFERENCES: N.Vergnolle, J. Immunol., 163, 5064 (1999); M.D.Hollenberg and M.Saifeddine, Can. J. Physiol. Pharmacol., 79, 439 (2001); Fang, J. et al. Blood 106, 2671(2005); Mulè, F. et al. Gut. 53, 229 (2004); Sekiguchi, F. et al. Drug Design Rev. 1, 287 (2004); Faruqi, T. et al.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?