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STEMCELL Technologies ME0328, Size: 1 mg
SDP

Supplier:  STEMCELL Technologies 1000271

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ME0328 is a cell-permeable and selective inhibitor of poly(ADP-ribose) polymerase 3 (PARP-3; IC₅₀ = 0.89 µM; Lindgren et al.). PARP-3 is required for stabilization of the mitotic spindle and crucial for mitotic progression (Sharif-Askari et al.). CANCER RESEARCH· Enhances vinorelbine-induced microtubule destabilization, leading to cell cycle arrest and apoptosis in breast cancer cells (Sharif-Askari et al.).

Catalog No. 50-204-5515


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