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AdipoGen Paxilline, 57186-25-1, MFCD00083464, 1 mg
SDP

Supplier:  AdipoGen AGCN20167M001

Encompass_Preferred

MF: C27H33NO4, MW: 435.6, ≥95%, Appearance: Off-white solid. Tremorgenic. Potent, selective and reversible inhibitor of high-conductance calcium-activated potassium (BKCa) channels. Reversible inhibitor of inositol 1,4,5-trisphosphate receptor (InsP(3)). Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) inhibitor. Liver X receptor (LXRalpha and LXRbeta; NR1H3 and NR1H2) agonist in biochemical and in vitro cell-based assays. Anticonvulsant. Apoptosis enhancer. Can sensitize various glioma cells to TRAIL-mediated apoptosis. Shown to protect neuronal cells against glutamate-induced cell death.

Catalog No. 50-596-431


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