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Selleck Chemical LLC Pazopanib S3012-1g

Supplier: Selleck Chemical LLC S30121G
Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1 VEGFR2 VEGFR3 PDGFR FGFR c-Kit and c-Fms/CSF1R with IC50 of 10 nM 30 nM 47 nM 84 nM 74 nM 140 nM and 146 nM in cell-free assays respectively Pazopanib induces cathepsin B activation and autophagy
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