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Medchemexpress LLC PD-118057 | 313674-97-4 | 98.06% | 386.27 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY10859410MG

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PD-118057 is an activator of the hERG channel that does not induce hERG blockade. It operates by activating the hERG channel, thereby helping to suppress changes in membrane excitability. Studies have shown that it specifically enhances hERG current and inhibits action potential duration in guinea pig ventricular muscle and cardiomyocytes. Additionally, it can reverse current inhibition caused by certain agents.

  • Activates the hERG channel without causing blockade.
  • Suppresses changes in membrane excitability.
  • Increases hERG current.
  • Inhibits action potential duration in ventricular muscle.
  • Reverses current inhibition induced by specific substances.

Catalog No. 50-003-45520


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