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Cayman Chemical PDD00017273 5mg
SDP

Supplier:  Cayman Chemical 195115 MG

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A PARG inhibitor (IC50 = 26 nM in an enzyme assay); maintains persistence of nuclear PAR chains in HeLa cells in the presence of the DNA damaging agent MMS (IC50 = 37 nM); increases nuclear γH2AX intensity in MCF-7 cells in a concentration-dependent manner when used in combination with MMS; reduces clonogenic growth of ZR-75-1 and MDA-MB-436 cells but not HCC1937 cells (IC50s = 0.2, 0.8, and >10 μM, respectively)

Catalog No. 50-298-2060


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