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Apexbio Technology LLC PDE4B-IN-2 915082-52-9 50mg

Supplier: Apexbio Technology LLC BA815950
PDE4B-IN-2 (CAS 915082-52-9) is a selective small molecule inhibitor targeting phosphodiesterase 4B (PDE4B) exhibiting an IC50 of 15 nM It demonstrates high selectivity by showing markedly reduced potency against the related isoform PDE4D (IC50 1 7 M) Through inhibition of PDE4B PDE4B-IN-2 modulates intracellular cyclic AMP levels offering a mechanistic basis for its anti-inflammatory properties This compound is suitable for investigating PDE4B-related signaling pathways and for exploring therapeutic strategies modulating inflammatory responses in preclinical research settings
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