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ABclonal Technology PE Rabbit anti-Mouse CD94 mAb
Supplier: ABclonal Technology A26470200T
CD94 is a 43 39 kD C-type lectin also known as Kp43 It is present on all NK cells NKT cells and a subset of CD8-positive T lymphocytes in most mouse strains CD94 is a type-II transmembrane protein with an extracellular lectin-like domain and a short cytoplasmic tail CD94 is expressed as a disulphide-linked heterodimer with a NKG2 subunit believed to mediate signal transduction When associated with NKG2A the complex triggers inhibition when associated with NKG2C the complex triggers stimulation The receptor complex of CD94 and NKG2 receptors bind to the ligand Qa-1 and are thought to play a role in maintaining self-tolerance in developing NK cells
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