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Apexbio Technology LLC Pefloxacin 70458-92-3 5mg
Supplier: Apexbio Technology LLC B12225
Pefloxacin (CAS 70458-92-3) is a small-molecule inhibitor targeting bacterial DNA gyrase (topoisomerase II) It is designed to inhibit this enzyme thereby disrupting DNA replication processes essential for bacterial proliferation Pefloxacin exerts its biological activity primarily through inhibition of bacterial DNA gyrase In in vitro studies Pefloxacin demonstrates inhibitory activity with reported IC50 values for DNA gyrase inhibition generally ranging from approximately 10 to 20 g/mL depending on bacterial strain and experimental conditions Based on these pharmacological properties Pefloxacin holds research potential in evaluating bacterial resistance DNA gyrase enzymatic assays antibiotic susceptibility assays and bacterial cell viability experiments
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