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Apexbio Technology LLC Pefloxacin Mesylate Dihydrate 149676-40-4 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B22915.1
Pefloxacin mesylate dihydrate is a third-generation fluoroquinolone antibacterial compound which functions through the inhibition of bacterial DNA gyrase (a type II DNA topoisomerase) By interfering with DNA gyrase activity pefloxacin mesylate dihydrate inhibits bacterial DNA replication and promotes bacterial cell death As an antibacterial agent this compound is commonly applied in biological research to study bacterial resistance pathways DNA gyrase inhibitory mechanisms and novel antimicrobial approaches In antimicrobial susceptibility assays pefloxacin mesylate displays inhibitory potency with reported IC50 values generally within the low micromolar range varying depending on bacterial strains and experimental conditions Researchers utilize this compound widely to investigate its antibacterial efficacy resistance development and mechanisms underlying drug-target interactions
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