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Medchemexpress LLC Pelcitoclax | 1619923-36-2 | 99.7% | 1281.85 | 1 ML

Supplier: Medchemexpress LLC HY10918550MG
Pelcitoclax (APG-1252) is a potent Bcl-2/Bcl-xl inhibitor with antineoplastic and pro-apoptotic effects. In vitro, APG-1252 changes to the reactive metabolite named APG-1252-M1, which has remarkable antitumor effects in acute myeloid leukemia. Pelcitoclax treatment inhibits xenograft tumor growth more obviously than other groups. In an animal model using BALB/c athymic nude mice, intravenous injection of Pelcitoclax once a day for 10 days inhibited xenograft tumor growth.
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