Cayman Chemical penIcIlum cItrInum cItrn 10mg

Supplier:  Cayman Chemical 1132010 MG

A mycotoxin with diverse biological activities; active against S. aureus, MRSA, rifampicin-resistant S. aureus, and vancomycin-resistant E. faecium (MICs = 1.95, 3.9, 0.97, and 7.81 UG/ml, respectively), as well as C. neoformans (MIC = 3.9 UG/ml); induces ROS production, mitochondrial membrane potential loss, and apoptosis in HepG2 cells at 30 µM and is cytotoxic to a variety of cells in vitro; reduces glutamate-induced excitotoxicity in primary rat cortical neurons at 0.1-1,000 nM; inhibits LPS-induced NO production in RAW 264.7 cells at 0.625-40 µM; toxic to brine shrimp larvae (LD50 = 96 UG/ml); toxic to rats and mice (oral LD50s = 50 and 87-105 mg/kg, respectively)

Catalog No. 50-295-1118