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Medchemexpress LLC Pentosan Polysulfate (Sodium) | 140207-93-8 | 5 MG
Supplier: Medchemexpress LLC HYA0203A5MG
Pentosan Polysulfate Sodium is an orally bioavailable, semi-synthetic medication with anti-inflammatory, pro-chondrogenic, and potent anti-HIV properties. It is used for the treatment of interstitial cystitis and is suitable for research applications.
- Inhibits HIV-1 activity and antigen expression
- Suppresses NF-κB and decreases proinflammatory actions of TNFα
- Reduces MCP-1 production stimulated by high glucose and advanced glycation end products (AGEs)
- Decreases interstitial inflammation and glomerulosclerosis in nephrectomized rats
- Preserves renal function and reduces albuminuria
- Mitigates severity of renal lesions, including tubulointerstitial inflammation
- Reduces upregulation of TNFα and proinflammatory genes in aging diabetic kidneys
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