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Medchemexpress LLC Pesampator | 1258963-59-5 | 99.9% | 392.49 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY11278110MG

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Pesampator is a potent and highly selective positive allosteric modulator of AMPA receptor (an AMPA potentiator) with an EC50 of 310 nM and a Ki of 170 nM.

  • Potent and highly selective positive allosteric modulator of AMPA receptor.
  • Increases CD-1 mouse cerebellum cGMP and decreases fall latency in C57BL/6J mice traversing an accelerating rotarod in vivo.
  • Reverses MK-801-mediated reduction in paired-pulse facilitation (PPF) in rats.
  • Attenuates ketamine-induced working memory disruptions in rats.
  • Affects the regional brain uptake of 2-deoxy-2-[18F]fluoro-d-glucose (FDG) in rats.

Catalog No. 50-004-37087


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