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Medchemexpress LLC PF-00356231 hydrochloride | 820223-77-6 | 99.5% | 464.96 | 10MM/1ML

Supplier: Medchemexpress LLC HY11409110MM/1ML
PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). It binds to MMP-12, forming a PF-00356231/MMP-12 complex. It shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC50s of 0.00065, 1.7, 0.98, 0.39 μM, respectively.
Features:
- MMP-12 inhibited with an IC50 of 1.4 μM
- MMP-13 inhibited with an IC50 of 0.65 nM
- MMP-3 inhibited with an IC50 of 0.39 μM
- MMP-8 inhibited with an IC50 of 1.7 μM
- MMP-9 inhibited with an IC50 of 0.98 μM
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