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Medchemexpress LLC PF-00835231 | 870153-29-0 | 99.3% | 472.53 | 100 MG
Supplier: Medchemexpress LLC HY137048100MG
PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM for SARS CoV-2 and 4 nM for SARS CoV-1 3CLpro. It is developed for the research of anti-SARS-CoV-2/COVID-19 and can inhibit cell infections as well as suppress infections in animal models.
- Acts as a CoV-2 cysteine 3C-like protease inhibitor.
- Shows potent inhibition against SARS CoV-2 and SARS CoV-1 3CLpro.
- Developed for research in anti-SARS-CoV-2/COVID-19.
- Capable of inhibiting cell infections.
- Demonstrates suppression of infections in animal models.
- Effectively inhibits SARS-CoV-2 USA-WA1/2020.
- Inhibits rhinovirus HRV3C protease.
- Reduces multifocal lung lesions and lung viral load in SARS-CoV-MA15 infected mouse models.
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