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Medchemexpress LLC PF-00835231 | 870153-29-0 | 99.31% | 472.53 | 50 MG
Supplier: Medchemexpress LLC HY13704850MG
PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively. It is developed for the research of anti-SARS-CoV-2/COVID-19, inhibiting cell infections and suppressing infections in animal models. It shows strong inhibitory effects and broad-spectrum activity against coronavirus Mp, with inhibitory effects against SARS-CoV-2 Wuhan, Washington strain 1, and Belgium/GHB-03021/2020 strain infections in various cell lines. It also reduces lung lesions and viral load in infected mouse models.
- CoV-2 cysteine 3C-like protease inhibitor
- Inhibits cell infections and suppresses infections in animal models
- Broad-spectrum activity against coronavirus Mp
- Effective against SARS-CoV-2 Wuhan, Washington strain 1, and Belgium/GHB-03021/2020 strain infections
- Reduces lung lesions and viral load in infected mouse models
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