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Medchemexpress LLC PF-06761281 | 1854061-19-0 | 99.5% | 50 MG
Supplier: Medchemexpress LLC HY12066950MG
Research-grade small-molecule inhibitor of the sodium-coupled citrate transporter (NaCT/SLC13A5) for in vitro and in vivo studies of citrate transport and metabolism. Supplied as an off-white to light yellow solid with high purity and characterized potency across cell-based and hepatocyte assays.
- Potent NaCT inhibitor with cellular IC50 ≈ 0.51 μM.
- Partial selectivity versus NaDC1 and NaDC3 (IC50 ≈ 13.2 μM and 14.1 μM).
- Demonstrated activity in hepatocytes (rat 0.12 μM, mouse 0.21 μM, human 0.74 μM).
- High purity solid, suitable for biochemical and pharmacology studies.
- Soluble in aqueous media at experimental concentrations; store sealed at -20°C.
- Available in small-mass quantities for research use.
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