Apexbio Technology LLC PF 1022A 133413-70-4 10mg

Supplier:  Apexbio Technology LLC B801810

PF 1022A (CAS 133413-70-4) is a cyclodepsipeptide exhibiting anthelmintic activity targeting latrophilin-like transmembrane receptors and nematode GABA receptor pathways It acts by interacting with these receptors affecting pharyngeal muscle activity in nematodes and modulating mammalian proteins such as p53 bax and p21 thereby impacting cell cycle regulation and apoptosis PF 1022A primarily exerts its biological activity as an ionophore facilitating ion transport across membranes In livestock experimental models PF 1022A demonstrates anthelmintic effects at doses of 1 10 mg/kg though precise IC50 values have not been established Based on these characteristics PF 1022A holds research potential in veterinary nematode control and as a tool for studying cell cycle regulation and apoptosis in vascular smooth muscle disease

Catalog No. 50-000-91170