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Medchemexpress LLC PF-4618433 | 1166393-85-6 | 98.62% | 445.52 | 100 MG
Supplier: Medchemexpress LLC HY18312100MG
PF-4618433 is a potent and selective PYK2 inhibitor, with an IC50 of 637 nM. It may be suitable for the research of osteoporosis, craniofacial and appendicular skeletal defects, and for targeted bone regeneration.
- Potent and selective PYK2 inhibitor.
- IC50 of 637 nM against PYK2.
- Promotes osteogenesis of hMSC cultures.
- Increases alkaline phosphatase (ALP) activity and mineralization.
- Enhances osteoblast proliferation.
- Enhances calcium deposition.
- Molecular weight: 445.52.
- Formula: C24H27N7O2.
- Appearance: Solid, white to off-white.
- Storage: Powder at -20°C for 3 years, 4°C for 2 years; in solvent at -80°C for 6 months, -20°C for 1 month.
- Purity: 98.62%.
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