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Selleck Chemical LLC PHA-767491 HCl S2742-10mg
Supplier: Selleck Chemical LLC S274210MG
PHA-767491 (CAY10572 NMS 1116354) HCl is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM in cell-free assays respectively It displays 20-fold selectivity against CDK1/2 and GSK3- 50-fold selectivity against MK2 and CDK5 100-fold selectivity against PLK1 and CHK2
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