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Medchemexpress LLC Phenol-amido-C1-PEG3-N3 (PROTAC Linker 21) | 1096439-18-7 | 99.9% | 50 MG
Supplier: Medchemexpress LLC HY12883550MG
Phenol-amido-C1-PEG3-N3 is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules possessing Alkyne groups. It can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent with an Azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reactions
- Undergoes strain-promoted alkyne-azide cycloaddition reactions
- PROTACs exploit the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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