Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Phensuximide | 86-34-0 | 99.4% | 5 MG
Supplier: Medchemexpress LLC HYB17305MG
Phensuximide is an orally active succinimide antiepileptic and anticonvulsant agent. It inhibits cyclic AMP and cyclic GMP accumulation in depolarized brain tissue and can be used for the study of seizure and petit mal.
- Orally active succinimide antiepileptic and anticonvulsant agent.
- Inhibits cyclic AMP and cyclic GMP accumulation in depolarized brain tissue.
- Produces depolarization-induced accumulation of cyclic GMP or cyclic AMP levels with ID50 values of 8.00 mM or 6.20 mM.
- Competitively inhibits mephenytoin 4-hydroxylase activity in human liver microsomes.
- Induces mild changes in renal function in Sprague-Dawley rats at 1.25 mmol/kg.
- Causes transient hematuria and proteinuria in Fischer 344 rats with daily administration (0.3 or 0.6 mmol/kg; 5-7 days).
- Appears as a solid, white to off-white substance.
- Soluble in DMSO at 100 mg/mL.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?