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Medchemexpress LLC Phenylephrine hydrochloride | 61-76-7 | 99.99% | 500 MG

Supplier: Medchemexpress LLC HYB0471500MG
Phenylephrine hydrochloride is a selective α1-adrenoceptor agonist, exhibiting pKis of 5.86, 4.87, and 4.70 for α1D, α1B, and α1A receptors respectively. It is intended for research use only.
- Promotes cardiac fibroblast proliferation and activates CaN, evoking NFAT3 nuclear translocation.
- Causes a rapid 12-fold activation of two p38-MAPK isoforms.
- Increases heart contractility.
- Activates SAPKs/JNKs in neonatal ventricular myocytes.
- Increases alveolar fluid clearance in high tidal volume-ventilated rats and accelerates pulmonary edema absorption.
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