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Medchemexpress LLC Phenytoin sodium | 630-93-3 | 99.8% | 1 ML
Supplier: Medchemexpress LLC HYB0448A10MM/1ML
Phenytoin sodium is a potent blocker of Voltage-gated Na+ channels (VGSCs). It demonstrates antiepileptic activity and has been observed to reduce breast tumor growth and metastasis in mice.
- Potent voltage-gated Na+ channels blocker
- Exhibits antiepileptic activity for partial and generalized tonic-clonic seizures
- Protects against seizures by voltage-dependent block of voltage-gated sodium channels
- Shows low affinity for resting sodium channels
- Greater binding and block occur in depolarized neurons with open/inactivated channels
- Displays strong use-dependent inhibitory potency
- Selectively inhibits pathological hyperexcitability
- Blocks persistent sodium current
- Acts as a Class 1b antiarrhythmic
- Reduces breast tumor growth and metastasis in mice
- Can induce a model of gingival hyperplasia in mice
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