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ABclonal Technology Phospho-Camk2-T286 Rabbit mAb
Supplier: ABclonal Technology AP1386100UL
The product of this gene belongs to the serine threonine protein kinases family and to the Ca(2 ) calmodulin-dependent protein kinases subfamily Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses This calcium calmodulin-dependent protein kinase is composed of four different chains alpha beta gamma and delta The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning In addition to its calcium-calmodulin (CaM)-dependent activity this protein can undergo autophosphorylation resulting in CaM-independent activity Several transcript variants encoding distinct isoforms have been identified for this gene
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