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ABclonal Technology Phospho-MST1-T183-MST2-T180
Supplier: ABclonal Technology AP1564100UL
This gene encodes a serine threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor Cleavage of the protein product by caspase removes the inhibitory C-terminal portion The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis Multiple transcript variants encoding different isoforms have been found for this gene
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