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Cayman Chemical PIrtobrutInIb 10mg
Supplier: Cayman Chemical 3677510 MG
A BTK inhibitor (IC50s = 10-100 and C481S, respectively); selective for BTK over EGFR (IC50 = 1-10 µM); decreases the number of Ki67-positive cells in MEC-1 CLL mouse xenograft models using MEC-1 cells that express either wild-type BTK or BTKC481S
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