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Medchemexpress LLC PKR-IN-C16 | 608512-97-6 | 99.7% | 268.29 | 1 MG
Supplier: Medchemexpress LLC HY13977A1MG
PKR-IN-C16 (Compound C16) is a specific double-stranded RNA-dependent protein kinase (PKR) inhibitor. It exhibits promising neuroprotective properties, can rescue acute brain lesions, and helps unlock translation blockade induced by PKR in primary neuronal cultures.
- Specific double-stranded RNA-dependent protein kinase (PKR) inhibitor
- Exhibits neuroprotective properties
- Rescues acute brain lesions
- Protects against neuronal cell death induced by endoplasmic reticulum stress
- Prevents PKR-phosphorylation and activation of caspase-3
- Reduces phosphorylated PKR levels
- Prevents PKR-induced neuronal loss and inflammatory response
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