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Cayman Chemical PlecnatIdeacetate 10mg
Supplier: Cayman Chemical 3387810 MG
A peptide agonist of the guanylate cyclase C receptor; stimulates cGMP production in T84 cells (EC50 = 170 nM); reduces increases in the number of neoplastic colon epithelial cells expressing Ki-67 induced by DSS in cancer-prone Apc+/Min-FCCC mice at 10 ppm in the diet; suppresses trinitrobenzenesulfonic acid-induced increases in abdominal contractions in a rat model of visceral hypersensitivity at 0.01 and 0.05 mg/kg
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