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Medchemexpress LLC PMX 205 | 514814-49-4 | 99.5% | 839.04 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY11013650MG

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PMX 205 is a potent complement C5a receptor (C5aR; CD88) antagonist. It is orally active and selective.

  • Potent complement C5a receptor (C5aR; CD88) antagonist
  • Orally active and selective C5aR antagonist
  • Extended survival time and reduced end-stage motor scores in a rat model of amyotrophic lateral sclerosis
  • Reduced astroglial proliferation in the lumbar spinal cord in a rat model of amyotrophic lateral sclerosis
  • Decreased fibrillar plaque load in Tg2576 mice and significantly reduced hyperphosphorylated tau in 3xTg mice in models of Alzheimer's disease

Catalog No. 50-003-45396


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