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Medchemexpress LLC PMX 205 Trifluoroacetate | 514814-49-4 | MFCD31735786 | 99.50% | 953.06 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY110136A

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PMX 205 Trifluoroacetate is a specific complement C5aR1 isoform antagonist.

  • Specific complement C5aR1 isoform antagonist.
  • Orally active (in vivo studies).
  • Has shown to extend survival time and reduce end-stage motor scores in a rat model of amyotrophic lateral sclerosis.
  • Reduces astroglial proliferation in the lumbar spinal cord in a rat model of amyotrophic lateral sclerosis.
  • Decreases fibrillar plaque load in murine models of Alzheimer's disease.
  • Reduces hyperphosphorylated tau in 3xTg mice.

Catalog No. 50-003-45910


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