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Medchemexpress LLC PMX 205 Trifluoroacetate | 514814-49-4 | MFCD31735786 | 99.50% | 953.06 | 25 MG

Supplier: Medchemexpress LLC 25MGHY110136A
PMX 205 Trifluoroacetate is a specific complement C5aR1 isoform antagonist.
- Specific complement C5aR1 isoform antagonist.
- Orally active (in vivo studies).
- Has shown to extend survival time and reduce end-stage motor scores in a rat model of amyotrophic lateral sclerosis.
- Reduces astroglial proliferation in the lumbar spinal cord in a rat model of amyotrophic lateral sclerosis.
- Decreases fibrillar plaque load in murine models of Alzheimer's disease.
- Reduces hyperphosphorylated tau in 3xTg mice.
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